Registered Nurses salary in Florence, SC

The median registered nurses in Florence, SC earns $81,170 a year, 17% below the US median. After tax that is roughly $5,089 a month.

10th percentile: $65,710
25th percentile: $66,860
Median percentile: $81,170
75th percentile: $125,840
90th percentile: $174,900

Based on 3,120 employed. Data period: BLS OEWS May 2025. Percentiles show the spread of pay, not experience; reading the 25th percentile as "entry level" is only an approximation.

What you keep

$61,063 take-home a year

Gross pay	$81,170
Federal income tax	−$9,027
Social Security + Medicare	−$6,210
South Carolina income tax (approx.)	−$4,870
Monthly take-home	$5,089
Every two weeks	$2,349

Does it go far here?

$93,542Median pay in Florence, SC is worth this at average US prices (local price level 86.8 vs 100).

18%of take-home pay goes to the median rent ($934 a month, Census ACS).

Top-paying jobs in Florence, SC

Job	Median pay
Medical and Health Services Managers	$118,750
General and Operations Managers	$99,520
First-Line Supervisors of Production and Operating Workers	$72,560
Industrial Machinery Mechanics	$63,840
First-Line Supervisors of Office and Administrative Support Workers	$61,750
Human Resources Specialists	$61,300
Secondary School Teachers, Except Special and Career/Technical Education	$60,950
Elementary School Teachers, Except Special Education	$60,910

All registered nurses salaries · Take-home pay in South Carolina