Physician Assistants salary in Sioux Falls, SD
The median physician assistants in Sioux Falls, SD-MN earns $135,790 a year, about the same as the US median. After tax that is roughly $8,673 a month.
- 10th percentile
- $106,660
- 25th percentile
- $110,150
- Median percentile
- $135,790
- 75th percentile
- $139,120
- 90th percentile
- $158,520
Based on 290 employed. Data period: BLS OEWS May 2025. Percentiles show the spread of pay, not experience; reading the 25th percentile as "entry level" is only an approximation.
What you keep
$104,078 take-home a year
| Gross pay | $135,790 |
| Federal income tax | −$21,324 |
| Social Security + Medicare | −$10,388 |
| South Dakota income tax (approx.) | −$0 |
| Monthly take-home | $8,673 |
| Every two weeks | $4,003 |
Does it go far here?
$149,827Median pay in Sioux Falls, SD is worth this at average US prices (local price level 90.6 vs 100).
12%of take-home pay goes to the median rent ($1,022 a month, Census ACS).
Top-paying jobs in Sioux Falls, SD
| Job | Median pay |
|---|---|
| Financial Managers | $163,580 |
| Pharmacists | $148,330 |
| General and Operations Managers | $142,730 |
| Nurse Practitioners | $130,390 |
| Lawyers | $112,260 |
| Software Developers | $101,040 |
| Civil Engineers | $99,700 |
| Computer Systems Analysts | $99,140 |
All physician assistants salaries · Take-home pay in South Dakota