Medical Assistants salary in Sioux Falls, SD
The median medical assistants in Sioux Falls, SD-MN earns $43,760 a year, 4% below the US median. After tax that is roughly $3,112 a month.
- 10th percentile
- $36,700
- 25th percentile
- $38,380
- Median percentile
- $43,760
- 75th percentile
- $46,700
- 90th percentile
- $49,540
Based on 620 employed. Data period: BLS OEWS May 2025. Percentiles show the spread of pay, not experience; reading the 25th percentile as "entry level" is only an approximation.
What you keep
$37,341 take-home a year
| Gross pay | $43,760 |
| Federal income tax | −$3,071 |
| Social Security + Medicare | −$3,348 |
| South Dakota income tax (approx.) | −$0 |
| Monthly take-home | $3,112 |
| Every two weeks | $1,436 |
Does it go far here?
$48,284Median pay in Sioux Falls, SD is worth this at average US prices (local price level 90.6 vs 100).
33%of take-home pay goes to the median rent ($1,022 a month, Census ACS).
Top-paying jobs in Sioux Falls, SD
| Job | Median pay |
|---|---|
| Financial Managers | $163,580 |
| Pharmacists | $148,330 |
| General and Operations Managers | $142,730 |
| Nurse Practitioners | $130,390 |
| Lawyers | $112,260 |
| Software Developers | $101,040 |
| Civil Engineers | $99,700 |
| Computer Systems Analysts | $99,140 |
All medical assistants salaries · Take-home pay in South Dakota